Transdermal Drug Delivery: Benefits and Challenges

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Transdermal Drug Delivery: Benefits and Challenges

Being the largest and most easily accessible organ of human body, the skin provides a painless and patient-friendly interface for systemic drug administration [1]. The creation of transdermal delivery systems is one of the most important innovations enabling the successful implementation of many of novel as well as conventional drugs [2]. Problems associated with the barrier properties of the s...

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Novel transdermal drug delivery systems

Background and aim: Eczema is a common inflammatory skin disease. Although history and physical examination are important in diagnosis of allergen, because of extent of environmental allergens, those are not simply recognized. The objective of this study was to determine allergens in patients with contact or atopic dermatitis referred to Razi hospital.Materials and Meth...

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Electrospun polymeric nanofibers for transdermal drug delivery

Conventional transdermal drug delivery systems (TDDS) have been designed for drug delivery through the skin. These systems use the permeability property of stratum corneum, the outermost surface layer of the skin. Applying polymeric micro and nanofibers in drug delivery has recently attracted great attention and the electrospinning technique is the preferred method for polymeric micro-nanofiber...

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Transdermal drug delivery.

Transdermal drug delivery is a validated technology contributing significantly to global pharmaceutical care. Since 1980, impressive growth in this field has been observed with many commercial successes; importantly, a new chemical entity was recently developed and approved for transdermal administration without having first been given as an injectable or oral dosage form. The progress achieved...

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Transdermal Drug Delivery

Overview For thousands of years, human civilizations have applied substances to the skin as cosmetic and medicinal agents.(Prausnitz 2008) However, it was not until the twentieth century that the skin came to be used as a drug delivery route. In fact, Merriam Webster dates the word “transdermal” to 1944(Merriam-Webster 2011) highlighting that it is a relatively recent concept in medical and pha...

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ژورنال

عنوان ژورنال: Journal of Applied Pharmacy

سال: 2016

ISSN: 1920-4159

DOI: 10.4172/1920-4159.1000e103